Research Blog
Peer-reviewed science, summarized. The Short Chain Aminos research blog tracks published third-party literature on the peptides and compounds our catalog supports — for laboratory research use only.

SLU-PP-332: An ERR Pan-Agonist — Chemistry and Discovery
A compound profile of SLU-PP-332, a synthetic small-molecule pan-agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ: its structure, its structure-based design at Saint Louis University,…
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5-Amino-1MQ: An NNMT Inhibitor — Chemistry and Discovery
A compound profile of 5-amino-1MQ (5-amino-1-methylquinolinium), a small cationic quinolinium that selectively inhibits nicotinamide N-methyltransferase (NNMT): structure, discovery through structure-activity work, and the enzyme it targets.
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Tesamorelin vs Ipamorelin: Structure and Receptor Pharmacology Compared
A molecular comparison of tesamorelin and ipamorelin: a 44-residue GHRH analog and a five-residue GHS-R1a agonist — their sequences, origins, receptor targets and analytical characterization, plus…
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KLOW Blend (GHK-Cu, BPC-157, TB-500, KPV): Composition and Analytical Profile
A composition profile of the KLOW blend: the four constituents GHK-Cu, BPC-157, TB-500 and KPV, what the stated total mass means, how the fixed ratio is…
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FOXO4-DRI: A D-Retro-Inverso Sequence Targeting the FOXO4–p53 Interaction
A compound profile of FOXO4-DRI: the D-retro-inverso design principle, the FOXO4–p53 protein interaction it was built to disrupt, structural studies of the p53 transactivation domain, and…
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SS-31 (Elamipretide): Structure, Membrane Binding and Target Identification
A compound profile of SS-31 (elamipretide): its four-residue aromatic-cationic sequence, its origin in the Szeto-Schiller series, its binding to the inner-membrane phospholipid diphosphatidylglycerol, and the CRISPR…
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GHK-Cu, BPC-157 and TB-500: A Molecular Comparison of Three Sequences
A side-by-side molecular comparison of GHK-Cu, BPC-157 and TB-500: sequences, molecular weights, origins, binding partners, and how single compounds and blends are characterized analytically.
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GHK-Cu: Copper Coordination Chemistry, Formulation and Stability
A chemistry profile of GHK-Cu: the copper(II) coordination of glycyl-L-histidyl-L-lysine, its discovery, its color and solution behavior, formulation and delivery considerations, and analytical characterization.
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Thymosin Alpha-1 (Thymalfasin): Structure, Discovery and Molecular Profile
A compound profile of thymosin alpha-1 (thymalfasin): its 28-residue acetylated sequence, its isolation from thymosin fraction 5, its structural behavior in solution, its reported receptor interactions,…
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How to Read a Certificate of Analysis (COA) for Research Peptides
A section-by-section guide to reading a certificate of analysis for research peptides — confirming identity by mass spectrometry, reading HPLC purity, checking methods, and matching the…
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MOTS-c, NAD+ and SS-31: Organelle-Associated Molecules Compared
A molecular comparison of MOTS-c, NAD+ and SS-31: a sequence encoded in the organelle genome, a dinucleotide redox cofactor, and an aromatic-cationic membrane-binding sequence — their…
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Melanotan-2 and the Melanocortin Receptor Family
A compound profile of Melanotan-2: a cyclic analog of α-MSH developed at the University of Arizona, its structure, the melanocortin receptor family it binds, and the…
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Planning Your Research Compound Supply: A Practical Guide
A practical guide to planning research-compound procurement — forecasting needs, allowing for synthesis and shipping lead times, vetting suppliers, and standardizing on documented, third-party-tested material.
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Transparent Pricing and Quality Standards for Research Peptides
How ShortChain Aminos approaches transparent pricing — no hidden fees, honest volume value through kits, and cost tied to published COAs for tested lots.
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Thymosin Alpha-1, KPV, Glutathione, NAD+ and Melanotan-2: A Molecular Overview
A molecular overview of five compounds — thymosin alpha-1, KPV, glutathione, NAD+ and Melanotan-2 — covering sequence or formula, origin, receptor or binding partner, and analytical…
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