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KLOW Blend (GHK-Cu, BPC-157, TB-500, KPV): Composition and Analytical Profile

Composition Profile · By SCA Team · 3 min read · Last updated October 5, 2026

Summary. KLOW is a single lyophilized vial containing four constituents — GHK-Cu, BPC-157, TB-500 and KPV — in a fixed ratio. This profile explains what each constituent is, what the stated total mass on the label means, how the ratio is verified on the certificate of analysis, and how KLOW relates to the three-component Glow blend.

1. Composition

Constituent Sequence / composition Approx. MW
GHK-Cu Gly-His-Lys complexed with Cu(II) ≈404 Da
BPC-157 GEPPPGKPADDAGLV ≈1,419 Da
TB-500 Synthetic thymosin β4 fragment centred on LKKTETQ per COA
KPV Lys-Pro-Val (three residues) ≈342 Da

The “80 mg” figure on the label is the total mass across all four constituents in the vial, not the mass of any single one. The individual amounts follow a fixed ratio, which should be checked against the lot’s certificate of analysis.

2. The constituents

GHK-Cu is the copper complex of glycyl-L-histidyl-L-lysine, first identified in human plasma; its Cu(II) center gives the blend a faint blue tint. BPC-157 is a 15-residue sequence derived from a protein found in gastric juice. TB-500 is based on the actin-binding region of thymosin β4. KPV is the C-terminal three-residue fragment (residues 11–13) of α-MSH.

3. KLOW and Glow compared

The Glow blend contains three constituents — GHK-Cu, BPC-157 and TB-500. KLOW adds KPV as a fourth. Because the total mass is shared across more components in KLOW, the amount of each shared constituent per vial differs between the two blends; the respective certificates of analysis list the exact figures.

4. Analytical characterization

Identity and purity are confirmed analytically for every lot. Reversed-phase HPLC with UV detection quantifies chromatographic purity, and electrospray mass spectrometry (ESI-MS) confirms that the observed molecular mass matches the theoretical value for each constituent.

For a multi-component vial, each constituent elutes as a separate chromatographic peak. The relative peak areas are compared against the labeled mass ratio, so the certificate of analysis can be checked constituent by constituent rather than as a single total.

Results are reported on a lot-specific certificate of analysis together with appearance, net content and the lot number, which allows any vial to be traced back to its analytical record.

5. Storage and handling

Material is supplied as a lyophilized solid in a sealed vial. Unopened vials are best kept at −20 °C, protected from light and moisture. Allow a vial to equilibrate to room temperature before opening to limit condensation, and record the lot number so the vial can be matched to its certificate of analysis.

KLOW and its constituents

A lot-specific certificate of analysis is available for each batch.

Research Use Only. All products sold by ShortChain Aminos are intended strictly for laboratory research purposes. They are not for human or veterinary use, and nothing in this article constitutes medical advice, usage instructions, or a recommendation of any kind. This content summarizes published third-party research for informational purposes only.

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